Comparative Antimicrobial, Phytochemical, Nutritional And Gc-Ms Profiling Of Methanolic Extracts Of Solanum Sect. Melongena
Author(s)
Abiola Grace Femi-Adepoju , Adeyinka Olufemi Adepoju , Ayo Emmanuel Fadiji , Ayanronke Suwebat Akinyemi , Felicia Adejoke Durodola ,
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Abstract
There is need for investigation into the relationship between organic chemical contents and various taxa of plants that exist. This study was conducted to further establish the biological importance of Solanum section Melongena which is beyond consumption. The antimicrobial screening was done by agar well diffusion. Bioactive, proximate and mineral components analyses were done by various spectrometry methods. The result of the antimicrobial screening showed that the plant species inhibited the test bacterial and fungal isolates with Solanum Indicum and Solanum Erianthum having the highest inhibition against Staphylococcus aureus, Candida albicans and Saccharomyces cerevisae. Higher content of alkaloid, saponin, terpenoids and cardiac glycoside and lower quantity of phenol, tannins, flavonoids and phlobatannin were detected in the plants extracts. GC-MS results showed the presence of phytoconstituents which supports the antimicrobial potentials of the plants, especially that of S. erianthum and S.indicum. The varieties were found to possess nutritional values and mineral contents such as high concentrations of Ca, K and Mg. These results revealed that the plants beyond their nutritional values possess strong antimicrobial properties and health benefits which can be useful in phytopharmaceutical and nutritherapy conditions in humans.
Keywords
Antimicrobial, Melongena, Phytopharmaceutical, Solanum, nutritherapy
References
i. Adepoju, A.O., Ogunkunle, A.T.J., Femi-Adepoju, A.G. (2014). Antifungal Activities of seed oil of Neem (Azadirachta indica A. Juss.). Global Journal of Biology, Agriculture and Health Sciences, 3(1): 126-131.
ii. Adepoju, A.O., Omotoso, I.O., Femi-Adepoju, A.G. and Karim, A.B. (2020). Comparative studies on the antimicrobial, chemical and biochemical contents of the foliar extracts of Capsicum fructescens L. Varieties. Afr. J. Biotech., 19(12): 836-845.
iii. Agoreyo, B.O., Obamas, E.S., Obanor, E.O. (2012). Comparative nutritional and phytochemical analyses of two varieties of Solanum melongena. Sci. World Journal, 7 (1): 2012. ISSN 1597-6343
iv. Ahmed, M., Ji, M., Sikandar, A., Iram, A., Qin, P., Zhu, H., Javeed, A., Shafi, J., Iqbal, Z., Farid, I.M. (2019). Phytochemical Analysis, Biochemical and Mineral Composition and GC-MS Profiling of Methanolic Extract of Chinese Arrowhead Sagittaria trifolia L. from Northeast China. Molecules, 24:3025. https://doi.org/10.3390/molecules24173025
v. Amadi, B., Onuoha, N., Amadi, C., Ugbogu, A., Duru, M. (2013). Elemental, amino acid and phytochemical constitute of fruit of three different species of eggplant. Int. Jr. of Med. & Aroma. Plants, 3(2):200-203.
vi. Ananda, A.D. (2012). Wound Case with Traditional Complementary and AlternativeMedicine. India Journal of Plastic Surgery, 45(2): 418-424. https://doi.org/10.4103/0970-0358.101331
vii. AOAC. Official Methods of Analysis; AOAC International: Arlington, VA, USA, 2000.
viii. Asaolu, S.S., Adefemi O.S., Oyakilome I.G., Ajibulu K.E., Asaolu M.F. (2012). Proximate and mineral composition of Nigerian leafy vegetables. J. Food Res.,1: 214.
ix. Asl, M.N., Hossein, H (2008). Review of Pharmacological Effects of Glycorrhiza sp. and its Bioactive compounds. Phytotherapy Research, 22: 709-724. https://doi.org/10.1002/ptr.2362
x. Association of Official Analytical Chemist. Official Method of Analysis International. 15th edition. Washington: USA. 1999; 127-136.
xi. Berma, S., Singh D., Verma, P., Soni, D., Gupta, A., Nema, R. (2013). Review Article Boerhavia diffusa: An Important medicinal plant and their phytochemistry. CMBT Jr of Sci. & Tech., 1(1):1-4.
xii. Bonsu, K.O, Fontem, D.A., Nkansah, G.O., Iruome, R.N., Owusu, E.O., Schippers, R.R. (2002) Diversity within the Gboma eggplant (Solanum marcocarpon), an indigenous vegetable from West Africa. Ghana. Jr. of Horticulture, 1:50-58.
xiii. Cushnie, T.P., Lamb, A.J. (2005). Antimicrobial activity of flavonoids. Int. J. Antimicrobial Agents. 26 (5):343–356. https://doi.org/10.1016/j.ijantimicag.2005.09.002
xiv. Dairo, K.P., Femi-Adepoju, A.G., Oke, C.O., Adio, A.A. (2016). Comparative Phytochemical and Antimicrobial Screening of Methanolic Extracts of Jatropha Curcas L. (igilapalapa) from Two Ecological Zones. Int. J. of Multidisciplinary and Current Research, 4: 29-34.
xv. Das, S. (2012). Antimicrobial activity study of ethanolic extract of Boerhaavia diffusa whole plant. International Journal of Pharmacy & Life Sciences, 3(10): 2006-2009.
xvi. Edem, C.A., Dounmu, M.I. Bassey, F.I., Wilson, C., Umoren, P. (2009). A comparative Assessment of the proximate composition, Ascorbic Acid and Heavy metal content of two species of Garden egg (Solanum gilo and Solanum aubergine). Pak. Jr. of Nutr., 8(5): 582-584. https://doi.org/10.3923/pjn.2009.582.584
xvii. Edeoga, H.O., Okwu, D.E., Mbaebie, B.O. (2005). Phytochemical Constiuents of some Nigerian medicinal plants. Afri. J. Biotechnol., 4 (7):685-688. https://doi.org/10.5897/ajb2005.000-3127.
xviii. Ekop, A.S. (2007). Determination of chemical composition of Gnetum africana (AFANG) seeds. Pak. Jr. of Nutr., 6(1):40-43. https://doi.org/10.3923/pjn.2007.40.43
xix. Fadiji, A.E., Omomowo, I., Omomowo, O., Lanrewaju, A., Akande, D. (2018). Antimicrobial efficacy andphytochemical screening of aqueous and ethanolic extracts of Ocimum gratissimum (scent leaf) leaf against some clinical isolates. Jr of Bas. Pharma. Toxicol. 2: 19-24.
xx. Femi-Adepoju, A.G., Fatoba, P.O., Adepoju, A.O., Oluyori, A.P. (2018b). Phytochemical Analysis, Antimicrobial Activity and Identification of Phytoconstituents in Gleichenia pectinata(Willd.) C. Presl. Int. Jr. of Biomed. & Adv. Res., 9(12): 400-406.
xxi. Femi-Adepoju, A.G., Adepoju, A.O., Durodola, F.A., Akanbi-Gada, M.A. (2018a). Phytochemical, Antimicrobial and Bio-Active Component Analysis of Platycerium Superbum (L.) Methanolic Extract. Inter. Jour. of Sci.: Bas. & Appl. Res., 40 (1): 98-107.
xxii. Femi-Adepoju, A.G., Adepoju, A.O., Ogunkunle, A.T.J. (2014). Assessment of the Fungicidal and Fungistatic properties of some Nigerian Moss Plants. Global Jr. of Biology, Agriculture & Health Sciences, 3(1): 106-109.
xxiii. Fernie, A.R., Trethewey, R.N., Krotzky, A.J., Willmitzer, L. (2004) Metaboliteprofiling: From diagnostics to systems biology. Nat Rev Mol Cell Biol., 5:763-769. https://doi.org/10.1038/nrm1451
xxiv. Ghorai, N., Chakraborty, S., Gucchait, S., Saha, S.K., Biswas, S. (2012). Estimation of total Terpenoids concentration in plant tissues using a monoterpene, Linalool as standard reagent. Nature protocol Exchange. https://doi.org/10.1038/protex.2012.055
xxv. Gill, L.S. (1992). Ethnomedicinal Uses of Plants in Nigeria. UNIBEN Press, Benin City, 275.
xxvi. Hambidge, M. (2006). Human zinc deficiency. Journal of Nutrtion, 130:1344S-1349S. https://doi.org/10.1093/jn/130.5.1344s
xxvii. Helena, E. (2008). Iron imbalance can lead to clinical depression. Jr. of Health and Fitness, 42: 48-102.
xxviii. Chinedu, S.N., Olasumbo, A.C., Eboji, O.K., Emiloju, O.C., Arinola, O.K., Dania, D.I. (2011). Proximate and phytochemical analysis of Solanum aethiopicum L and Solanum macrocarpon L. fruits. Res. Jr. of Chem. Sci., 1: 63-71.
xxix. Igwe, S.A., Akunyili, D.N., Ogbogu, C. (2003). Effects of Solanum melongena on some visual functions of visually active Igbos of Nigeria. Jr. of Ethnopharmacology, 86:135-138. https://doi.org/10.1016/s0378-8741(02)00364-1
xxx. Kell, D.B., Brown, M., Davey, H.M., Dunn, W.B., Spasic, I., Oliver, S.G. (2005). Metabolic footprinting and systems biology: The medium is the message. Nat. Rev. Microbiol., 3:557-565. https://doi.org/10.1038/nrmicro1177
xxxi. Khan, M.S., Ansari, I.A., Ahmad, S., Akhtar, F., Hashim, A., Srivastava, A.K. (2013). Chemotherapeutic potential of Boerhaavia diffusa Linn; A review. Journal of Applied Pharmaceutical Sciences. 3(01):133-139. https://doi.org/10.7324/japs.2013.30126
xxxii. Krishnaiah, D., Devi, T., Bono, A., Sarbatly, R. (2008). Studies on phytochemical constituents of six Malaysian medicinal plants. Jr of Med. Plants. Res., 3(2): 67-72.
xxxiii. Krishnamoorthy, K., Subramaniam, P. (2014). Phytochemical Profiling of Leaf, Stem, and Tuber Parts of Solena amplexicaulis (Lam.) Gandhi Using GC-MS. Int. Sch. Res. Notices, 2014:567409. https://doi.org/10.1155/2014/567409
xxxiv. Lichtenstein, A.H., Appel, L.J., Brands, M., Carnethon, M., Daniels, S., Franch H.A., Franklin B., Kris-Etherton P., Harris W.S., Howard B., Karanja N., Lefevre M., Rudel L., Sacks F., Van Horn L., Winston M., Wylie-Rosett J. (2006). Summary of American heart association diet and lifestyle recommendations revision. Arteriosclerosis, Thrombosis and Vascular Biology, 26: 2186-2191. https://doi.org/10.1161/01.atv.0000238352.25222.5e
xxxv. Manoko, M.L.K., van der Weerden, G.M. (2004) Solanum americanum In: G. J. H. Grubben and O. A. Denton (eds.), Plant Resources of Tropical Africa 2. Vegetables. PROTA Foundation Wageningen / CTA Wageningen, Backhuys Publishers, Leiden, the Netherlands, pp. 477-480.
xxxvi. Mohamed, I.E., EL-Nur E.B., Choudhary, M.I., Khan, S.N. (2009). Bioactive natural products from two Sudanese Medicinal plants Diospyros mespiliformis and Crotonzambesic us. Natural Products Research, 3(4):198-203.
xxxvii. Nelso, D.L., Cox, M.M. (2005). Lehninger Principle of Biochemistry, 4th ed. W.H. Freeman. https://doi.org/10.1002/bmb.2005.494033010419
xxxviii. Newman, D.J., Cragg, G.M. (2007). Natural Products as Sources of New Drugs over the last 25 Years. Jr of Nat. Prod., 70(3):461-477. https://doi.org/10.1021/np068054v
xxxix. Odetola, A.A., Iranloye, Y.O., Akinloye, O. (2004). Hypolipidemic Potentials of Solanum melongena and Solanum gilo on Hypercholesterolemic Rabbits. Pak. Jr. of Nutri. 3: 180-187. https://doi.org/10.3923/pjn.2004.180.187
xl. Peng, J.P., Kobayasli H. (1995). Novel furastonol glycosides from Allium anacros tenon plant. Media., 6: 58-61.https://doi.org/10.1055/s-2006-958000
xli. Sofowora, A. (1993). Medicinal Plants and Traditional Medicine in Africa Spectrum Books Ltd.Ibadan Nigeria.Pp. 191 –289.
xlii. Street, R.A., Prinsloo, G. (2013). Commercially Important Medicinal Plants in South Africa:A Review. Journal of Chemistry 16. Article ID 205048. https://doi.org/10.1155/2013/205048
xliii. Vance, C.P., Uhde-Stone, C., Allan, D.L. (2003). Phosphorus acquisition and use: critical adaptations by plants for securing anon renewable resource. New Phytologist, 157: 432–449. https://doi.org/10.1046/j.1469-8137.2003.00695.x
xliv. Wu, Y.Y., Li, W., Xu, Y., Jin, E.H., Tu, Y.Y. (2011). Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence and DNA damage analyses. Jr. of Zhej. Uni. Sci., 12:744.https://doi.org/10.1631/jzus.b1100041.
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